Reboot does not reset the message bus.

DWSupport states that "clearing the messagebus queue is separate and it is not included in a...reboot"

So don't trust that periodic reboots will clear it and if you think it needs resetting, do it manually!

Dear Jon Neff! It looks like the Community cannot answer your question. That's why we have opened a Support Request with the Number SR-128296-T1H7Y for you. A Software Support Specialist will contact you directly to follow up. We will update this thread with the solution as soon as we have resolved the Support Request. With best regards, DocuWare Support Team